Inverse association between methylation of human papillomavirus type 16 DNA and risk of cervical intraepithelial neoplasia grades 2 or 3.

The clinical relevance of human papillomavirus type 16 (HPV16) DNA methylation has not been well documented, although its role in modulation of viral transcription is recognized.Study subjects were 211 women attending Planned Parenthood clinics in Western Washington for routine Papanicolaou screenin...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Long Fu Xi, Mingjun Jiang, Zhenping Shen, Ayaka Hulbert, Xiao-Hua Zhou, Ying-Ying Lin, Nancy B Kiviat, Laura A Koutsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Online Access:http://europepmc.org/articles/PMC3161083?pdf=render