Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer

Abstract Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their behavior is regulated through a complex interplay of networks, including transcriptional, post-transcriptiona...

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Bibliographic Details

Published in:	Molecular Cancer
Main Authors:	Zhen Zeng, Minyang Fu, Yuan Hu, Yuquan Wei, Xiawei Wei, Min Luo
Format:	Article
Language:	English
Published:	BMC 2023-10-01
Subjects:	CSCs Regulatory networks Cancer therapy
Online Access:	https://doi.org/10.1186/s12943-023-01877-w