Population pharmacokinetic modeling of sulfadimethoxine, sulfadiazine and sulfamethoxazole combined to trimethoprim in pigs

Sulfonamides (S) are old antibiotics combined with trimethoprim (TMP) for synergistic effects against pathogens responsible for a variety of infections in food-producing animals. In growing pigs, the TMP:S ratio is 1:5 based on human TMP/sulfamethoxazole (SMX) dosing which aims to obtain an in vivo...

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Bibliographic Details

Published in:	Veterinary Quarterly
Main Authors:	Marine Boulanger, Jean-François Taillandier, Jérôme Henri, Mathias Devreese, Siegrid De Baere, Marlène Lacroix, Aude A. Ferran, Alexis Viel
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Combination dosage regimen population pharmacokinetic modeling pigs
Online Access:	https://www.tandfonline.com/doi/10.1080/01652176.2025.2565351