UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons

The dysregulation of genes in neurodevelopmental disorders that lead to social and cognitive phenotypes is a complex, multilayered process involving both genetics and epigenetics. Parent-of-origin effects of deletion and duplication of the 15q11-q13 locus leading to Angelman, Prader-Willi, and Dup15...

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Bibliographic Details

Published in:	Epigenetics
Main Authors:	S. Jesse Lopez, Keith Dunaway, M. Saharul Islam, Charles Mordaunt, Annie Vogel Ciernia, Makiko Meguro-Horike, Shin-ichi Horike, David J. Segal, Janine M. LaSalle
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-11-01
Subjects:	autism chromatin dna methylation epigenetic imprinting histone modification
Online Access:	http://dx.doi.org/10.1080/15592294.2017.1376151