Structural Investigation of the Interaction Mechanism between Chlorogenic Acid and AMPA Receptor via In Silico Approaches

Chlorogenic acid (CGA), an important metabolite in natural plant medicines such as honeysuckle and eucommia, has been shown to have potent antinociceptive effects. Nevertheless, the mechanism by which CGA relieves chronic pain remains unclear. α-amino-3-hydroxy-5-methyl-4-isooxazolpropionic acid rec...

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書誌詳細

出版年:	Molecules
主要な著者:	Wei Zhu, Fengming Wu, Jindie Hu, Wenjing Wang, Jifeng Zhang, Guoqing Guo
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2022-05-01
主題:	chlorogenic acid GluA1 chronic pain molecular docking molecular dynamics simulation
オンライン･アクセス:	https://www.mdpi.com/1420-3049/27/11/3394