Volumetric analysis of the terminal ductal lobular unit architecture and cell phenotypes in the human breast

Summary: The major lactiferous ducts of the human breast branch out and end at terminal ductal lobular units (TDLUs). Despite their functional and clinical importance, the three-dimensional (3D) architecture of TDLUs has remained undetermined. Our quantitative and volumetric imaging of healthy human...

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Bibliographic Details
Published in:Cell Reports
Main Authors: Oona Paavolainen, Markus Peurla, Leena M. Koskinen, Jonna Pohjankukka, Kamyab Saberi, Ella Tammelin, Suvi-Riitta Sulander, Masi Valkonen, Larissa Mourao, Pia Boström, Nina Brück, Pekka Ruusuvuori, Colinda L.G.J. Scheele, Pauliina Hartiala, Emilia Peuhu
Format: Article
Language:English
Published: Elsevier 2024-10-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724011884