Efficacy of baloxavir marboxil as a prophylactic against influenza among in-patients and analysis of influenza virus mutations in their isolates at a Japanese hospital during the 2023–2024 flu season

Abstract Background Baloxavir marboxil (baloxavir) is a new anti-influenza drug that works as a cap-dependent endonuclease inhibitor. It is approved for prophylactic use against influenza in Japan, but there are few reports on this usage in hospitalized in-patients. It reportedly reduces patient sus...

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Bibliographic Details

Published in:	Journal of Pharmaceutical Health Care and Sciences
Main Authors:	Akihide Fujii, Tomohiro Oishi, Eisei Kondo, Zyunko Morihara, Yuka Ikeda, Hideyuki Sumida, Youko Ninomiya, Satoe Uesugi, Kimie Okazaki, Daisuke Yoshioka, Miyoko Kobayashi, Hideho Wada
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Subjects:	Baloxavir marboxil Hospital Prophylaxis Mutation
Online Access:	https://doi.org/10.1186/s40780-025-00418-5