DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection

ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-6A, HHV-6B or HHV-7 is able to modify DNA sen...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Daria Bortolotti, Valentina Gentili, Elisabetta Caselli, Mariangela Sicolo, Irene Soffritti, Maria D’Accolti, Isabel Barao, Antonella Rotola, Dario Di Luca, Roberta Rizzo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-02-01
Subjects:	DNA sensors human herpesvirus natural killer cells HHV-6A HHV-6B HHV-7
Online Access:	https://www.frontiersin.org/article/10.3389/fmicb.2020.00226/full