Usher syndrome type 1-associated gene, pcdh15b, is required for photoreceptor structural integrity in zebrafish

Blindness associated with Usher syndrome type 1 (USH1) is typically characterized as rod photoreceptor degeneration, followed by secondary loss of cones. The mechanisms leading to blindness are unknown because most genetic mouse models only recapitulate auditory defects. We generated zebrafish mutan...

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Bibliographic Details

Published in:	Disease Models & Mechanisms
Main Authors:	Amanda Miles, Clarke Blair, Andrew Emili, Vincent Tropepe
Format:	Article
Language:	English
Published:	The Company of Biologists 2021-12-01
Subjects:	calyceal processes outer segment retina usher syndrome zebrafish photoreceptor
Online Access:	http://dmm.biologists.org/content/14/12/dmm048965