Detecting fitness epistasis in recently admixed populations with genome-wide data

Abstract Background Fitness epistasis, the interaction effect of genes at different loci on fitness, makes an important contribution to adaptive evolution. Although fitness interaction evidence has been observed in model organisms, it is more difficult to detect and remains poorly understood in huma...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:BMC Genomics
المؤلفون الرئيسيون: Xumin Ni, Mengshi Zhou, Heming Wang, Karen Y. He, Uli Broeckel, Craig Hanis, Sharon Kardia, Susan Redline, Richard S. Cooper, Hua Tang, Xiaofeng Zhu
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2020-07-01
الموضوعات:
Fitness epistasis
Admixed population
Admixture linkage disequilibrium
Co-evolution
Diseases/traits
الوصول للمادة أونلاين:http://link.springer.com/article/10.1186/s12864-020-06874-7

الانترنت

http://link.springer.com/article/10.1186/s12864-020-06874-7

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