Pathophysiology of diabetes mellitus type 2: beyond the duo "insulin resistance-secretion deficit"

T2DM involves at least two primary pathogenic mechanisms: (a) a progressive decline in pancreatic islet cell function resulting in reduced insulin secretion and (b) peripheral insulin resistance resulting in a decrease in the metabolic responses to insulin. This dynamic interaction between insulin s...

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Bibliographic Details

Published in:	Nutrición Hospitalaria
Main Authors:	C. A. Carrera Boada, J. M. Martínez-Moreno
Format:	Article
Language:	English
Published:	Arán Ediciones, S. L. 2013-01-01
Subjects:	Diabetes Resistencia a la insulina Glucosa
Online Access:	http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000800012&lng=en&tlng=en