Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida.

Pasteurella multocida can infect a multitude of wild and domesticated animals, with infections in cattle resulting in hemorrhagic septicemia (HS) or contributing to bovine respiratory disease (BRD) complex. Current cattle vaccines against P. multocida consist of inactivated bacteria, which only offe...

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Bibliographic Details
Published in:PLoS Pathogens
Main Authors: Epshita A Islam, Jamie E Fegan, Takele A Tefera, David M Curran, Regula C Waeckerlin, Dixon Ng, Sang Kyun Ahn, Chun Heng Royce Lai, Quynh Huong Nguyen, Megha Shah, Liyuwork Tesfaw, Kassaye Adamu, Wubet W Medhin, Abinet Legesse, Getaw Deresse, Belayneh Getachew, Neil Rawlyk, Brock Evans, Andrew Potter, Anthony B Schryvers, Scott D Gray-Owen, Trevor F Moraes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Online Access:https://doi.org/10.1371/journal.ppat.1011249