A Critical Role for the Mitochondrial Pyruvate Carrier in Hepatic Stellate Cell ActivationSummary

Background & Aims: Hepatic stellate cells (HSCs) are non-parenchymal cells of the liver that produce the extracellular matrix that forms fibrotic lesions in chronic liver disease, including metabolic dysfunction-associated steatohepatitis (MASH). The mitochondrial pyruvate carrier (MPC) cata...

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出版年:	Cellular and Molecular Gastroenterology and Hepatology
主要な著者:	Mohammad Habibi, Daniel Ferguson, Sophie J. Eichler, Mandy M. Chan, Christina Fu, Terri A. Pietka, Andrea L. Bredemeyer, Andrew LaPoint, Trevor M. Shew, Mai He, Kim H.H. Liss, Andrew J. Lutkewitte, Kevin Cho, Joel D. Schilling, Gary J. Patti, Brian N. Finck
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2025-01-01
主題:	Collagen Fibrosis HIF1alpha MASLD TCA Cycle
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2352345X2500058X