Fitness of B-Cell Responses to SARS-CoV-2 WT and Variants Up to One Year After Mild COVID-19 – A Comprehensive Analysis

ObjectiveTo comprehensively evaluate SARS-CoV-2 specific B-cell and antibody responses up to one year after mild COVID-19.MethodsIn 31 mildly symptomatic COVID-19 participants SARS-CoV-2-specific plasmablasts and antigen-specific memory B cells were measured by ELISpot. Binding antibodies directed a...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Benjamin Meyer, Paola Andrea Martinez-Murillo, Barbara Lemaitre, Géraldine Blanchard-Rohner, Arnaud M. Didierlaurent, Paola Fontannaz, Chloé Eugercios Manzanas, Paul-Henri Lambert, Natasha Loevy, Laurent Kaiser, Julie Sartoretti, Chantal Tougne, Jean Villard, Angela Huttner, Claire-Anne Siegrist, Christiane S. Eberhardt
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Subjects:	SARS-CoV-2 plasmablasts memory B cells antibody response COVID-19 neutralization
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.841009/full