Specificity of the HIV-1 Protease on Substrates Representing the Cleavage Site in the Proximal Zinc-Finger of HIV-1 Nucleocapsid Protein

To explore the sequence context-dependent nature of the human immunodeficiency virus type 1 (HIV-1) protease’s specificity and to provide a rationale for viral mutagenesis to study the potential role of the nucleocapsid (NC) processing in HIV-1 replication, synthetic oligopeptide substrates represen...

Full description

Bibliographic Details

Published in:	Viruses
Main Authors:	János András Mótyán, Márió Miczi, Stephen Oroszlan, József Tőzsér
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Subjects:	human immunodeficiency virus HIV-1 protease viral proteases specificity viral proteins
Online Access:	https://www.mdpi.com/1999-4915/13/6/1092