Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia

Abstract Acute lung injury (ALI) is generally caused by severe respiratory infection and characterized by overexuberant inflammatory responses and inefficient pathogens-containing, the two major processes wherein alveolar macrophages (AMs) play a central role. Dysfunctional mitochondria have been li...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Lusha Ye, Yanan Gao, Simon Wing Fai Mok, Wucan Liao, Yazhou Wang, Changjiang Chen, Lijun Yang, Junfeng Zhang, Liyun Shi
Format:	Article
Language:	English
Published:	BMC 2024-04-01
Subjects:	Artemisia-derived nanovesicles Alveolar macrophages Acute lung injury Gamma-aminobutyric acid Mitochondrial function
Online Access:	https://doi.org/10.1186/s12951-024-02473-w