Natural selection and recombination at host-interacting lipoprotein loci drive genome diversification of Lyme disease and related bacteria

ABSTRACT Lyme disease, caused by spirochetes in the Borrelia burgdorferi sensu lato clade within the Borrelia genus, is transmitted by Ixodes ticks and is currently the most prevalent and rapidly expanding tick-borne disease in Europe and North America. We report complete genome sequences of 47 isol...

Full description

Bibliographic Details

Published in:	mBio
Main Authors:	Saymon Akther, Emmanuel F. Mongodin, Richard D. Morgan, Lia Di, Xiaohua Yang, Maryna Golovchenko, Natalie Rudenko, Gabriele Margos, Sabrina Hepner, Volker Fingerle, Hiroki Kawabata, Ana Cláudia Norte, Isabel Lopes de Carvalho, Maria Sofia Núncio, Adriana Marques, Steven E. Schutzer, Claire M. Fraser, Benjamin J. Luft, Sherwood R. Casjens, Weigang Qiu
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-09-01
Subjects:	Borrelia burgdorferi recombination Lyme disease evolution genome diversification plasmids
Online Access:	https://journals.asm.org/doi/10.1128/mbio.01749-24