Formulation of zein nanoparticles for augmenting the anti-inflammatory activity of dexketoprofen

IntroductionTopical delivery of anti-inflammatory drugs is an important strategy for enhancing therapeutic efficacy while minimizing systemic side effects. This study focuses on improving the anti-inflammatory activity of Dexketoprofen by developing zein nanoparticles (ZNs) as a novel topical carrie...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Mahmoud A. El Hassab, Mona H. Ibrahim, Sherif S. Abdel Mageed, Abdulla M. A. Mahmoud, Zainab Sabry Othman Ahmed, Shaimaa Mosallam, Manar Adel Abdelbari, Eman F. Khaleel, Maram A. El Hasab, Asmaa Elsayyad, Shady Allam, Moaz A. Eltabeeb, Ahmed T. Negmeldin, Wagdy M. Eldehna, Rofida Albash
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	dexketoprofen zein nanoparticles inflammation formalin-induced paw edema topical delivery docking
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1560585/full