A proteomics investigation of primary human articular chondrocyte isolation

Objective: Human primary articular chondrocytes (hPACs) are routinely isolated from articular cartilage for pre-clinical OA research. Collagenase digest of tissue is an essential step, yet the impact of lengthy enzymatic incubation on the hPAC phenotype is unclear. We aimed to delineate this through...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Osteoarthritis and Cartilage Open
المؤلفون الرئيسيون: Abby Brumwell, Simran Raheja, William Cawley, Emily Birkett-Jones, Sarah E. Orr, Caitlin Todd, David J. Deehan, Nichola J. Conlon, Matthias Trost, Sarah J. Rice
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Elsevier 2025-12-01
الموضوعات:
Collagenase
Osteoarthritis
Chondrocytes
Phenotype
Proteomic
Transcriptomic
الوصول للمادة أونلاين:http://www.sciencedirect.com/science/article/pii/S2665913125001001

الانترنت

http://www.sciencedirect.com/science/article/pii/S2665913125001001

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