The Dihydrouridine landscape from tRNA to mRNA: a perspective on synthesis, structural impact and function

The universal dihydrouridine (D) epitranscriptomic mark results from a reduction of uridine by the Dus family of NADPH-dependent reductases and is typically found within the eponym D-loop of tRNAs. Despite its apparent simplicity, D is structurally unique, with the potential to deeply affect the RNA...

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Bibliographic Details

Published in:	RNA Biology
Main Authors:	Olivier Finet, Carlo Yague-Sanz, Florian Marchand, Damien Hermand
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2022-12-01
Subjects:	rna modification dihydrouridine dus epitranscriptome
Online Access:	http://dx.doi.org/10.1080/15476286.2022.2078094