Mitochondrial Transplantation Therapy Ameliorates Muscular Dystrophy in <i>mdx</i> Mouse Model

Duchenne muscular dystrophy is caused by loss of the dystrophin protein. This pathology is accompanied by mitochondrial dysfunction contributing to muscle fiber instability. It is known that mitochondria-targeted in vivo therapy mitigates pathology and improves the quality of life of model animals....

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Mikhail V. Dubinin, Irina B. Mikheeva, Anastasia E. Stepanova, Anastasia D. Igoshkina, Alena A. Cherepanova, Alena A. Semenova, Vyacheslav A. Sharapov, Igor I. Kireev, Konstantin N. Belosludtsev
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Subjects:	Duchenne muscular dystrophy skeletal muscle mitochondrial dysfunction mitochondrial transplantation lipid peroxidation muscle force
Online Access:	https://www.mdpi.com/2218-273X/14/3/316