Learning the sequence of influenza A genome assembly during viral replication using point process models and fluorescence in situ hybridization.

Within influenza virus infected cells, viral genomic RNA are selectively packed into progeny virions, which predominantly contain a single copy of 8 viral RNA segments. Intersegmental RNA-RNA interactions are thought to mediate selective packaging of each viral ribonucleoprotein complex (vRNP). Clea...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Timothy D Majarian, Robert F Murphy, Seema S Lakdawala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Online Access:http://europepmc.org/articles/PMC6366722?pdf=render