Sigma-1 receptor exerts protective effects on ameliorating nephrolithiasis by modulating endoplasmic reticulum-mitochondrion association and inhibiting endoplasmic reticulum stress-induced apoptosis in renal tubular epithelial cells

Oxalate-induced damage to renal tubular epithelial cells (RTECs) is an essential factor in the incident kidney stone, but the specific mechanism is unclear. Recent research has pinpointed interacting areas within the endoplasmic reticulum and mitochondria, called mitochondria-associated membranes (M...

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Bibliographic Details

Published in:	Redox Report
Main Authors:	Hu Ke, Xiaozhe Su, Caitao Dong, Ziqi He, Qianlin Song, Chao song, Jiawei Zhou, Wenbiao Liao, Chuan Wang, Sixing Yang, Yunhe Xiong
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Subjects:	Sigmar-1 receptor endoplasmic reticulum stress kidney stone apoptosis dimemorfan mitochondria-associated endoplasmic reticulum membrane
Online Access:	https://www.tandfonline.com/doi/10.1080/13510002.2024.2391139