Comprehensive analysis of the tumor targeting efficiency of functionalized nanoparticles in an immunocompetent environment

Abstract The success of nanoparticle-based cancer therapeutics relies on their efficient tumor uptake and retention. Given this, improving nanoparticle localization in tumors is paramount to maximize their therapeutic potential. A common approach to achieve this is to functionalize nanoparticles wit...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Nolan Jackson, Nasry Bouzeineddine, Daniel Cecchi, Safara Holder, Katrina Gee, Wayne Beckham, Sameh Basta, Sunil Krishnan, Devika B. Chithrani
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-10-01
Online Access:	https://doi.org/10.1038/s41598-025-22151-7