Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions

Here, we have unveiled the effects of cycloastragenol against Aβ (Amyloid-beta)-induced oxidative stress, neurogenic dysfunction, activated mitogen-activated protein (MAP) kinases, and mitochondrial apoptosis in an Aβ-induced mouse model of Alzheimer’s disease (AD). The Aβ-induced mouse model was de...

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Bibliographic Details

Published in:	Cells
Main Authors:	Muhammad Ikram, Myeung Hoon Jo, Kyonghwan Choe, Amjad Khan, Sareer Ahmad, Kamran Saeed, Min Woo Kim, Myeong Ok Kim
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	Alzheimer’s disease Amyloid-beta neurogenesis neuroprotection neurodegeneration
Online Access:	https://www.mdpi.com/2073-4409/10/10/2719