Causal association of genetically determined plasma metabolites with osteoarthritis: a two-sample Mendelian randomization study

BackgroundWe aimed to elucidate the causal relationship between plasma metabolites and the vulnerability to Osteoarthritis (OA), encompassing both hip OA and knee OA.MethodsWe conducted a two-way two-sample Mendelian randomization (MR) analysis to investigate the association of 1,400 plasma metaboli...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Qingsong Fu, Xinhua Yuan, Weibin Wang, Xinyou Han, Jiakai Zhang, Junlong Wu, Yao Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-06-01
Subjects:	metabolites osteoarthritis Mendelian randomization causal two-sample
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1396746/full