Significance of TP53, CDKN2A, SMAD4 and KRAS in Pancreatic Cancer

The present review demonstrates the major tumor suppressor genes, including TP53, CDKN2A and SMAD4, associated with pancreatic cancer. Each gene’s role, prevalence and impact on tumor development and progression are analyzed, focusing on the intricate molecular landscape of pancreatic cancer. In add...

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Bibliographic Details

Published in:	Current Issues in Molecular Biology
Main Authors:	Dimitrios Stefanoudakis, Maximos Frountzas, Dimitrios Schizas, Nikolaos V. Michalopoulos, Alexandra Drakaki, Konstantinos G. Toutouzas
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Subjects:	TP53 CDKN2A SMAD4 KRAS pancreatic cancer PDAC
Online Access:	https://www.mdpi.com/1467-3045/46/4/177