A Neuroligin-1 mutation associated with Alzheimer’s disease produces memory and age-dependent impairments in hippocampal plasticity

Summary: Alzheimer’s disease (AD) is characterized by memory impairments and age-dependent synapse loss. Experimental and clinical studies have shown decreased expression of the glutamatergic protein Neuroligin-1 (Nlgn1) in AD. However, the consequences of a sustained reduction of Nlgn1 are unknown....

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Bibliographic Details

Published in:	iScience
Main Authors:	Francisco Arias-Aragón, Enriqueta Tristán-Clavijo, Irene Martínez-Gallego, Estefanía Robles-Lanuza, Heriberto Coatl-Cuaya, Celia Martín-Cuevas, Ana C. Sánchez-Hidalgo, Antonio Rodríguez-Moreno, Amalia Martinez-Mir, Francisco G. Scholl
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Subjects:	Behavioral neuroscience Molecular neuroscience Cellular neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223009458