Role of B-Cell in the Pathogenesis of Systemic Sclerosis

Systemic sclerosis (SSc) is a rare multisystem autoimmune disease, characterized by fibrosis, vasculopathy, and autoimmunity. Recent advances have highlighted the significant implications of B-cells in SSc. B-cells are present in affected organs, their subpopulations are disrupted, and they display...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Benjamin Thoreau, Benjamin Chaigne, Luc Mouthon
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Subjects:	systemic sclerosis B-cell pathogenesis B-cell receptor (BCR) interleukine 6 (IL-6) autoantibodies
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.933468/full