The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice

Abstract: Venous thromboembolism (VTE) is a leading cause of morbidity and mortality in elderly people. Increased expression of tumor suppressor protein 53 (p53) has been implicated in vascular senescence. Here, we examined the importance of endothelial p53 for venous thrombosis and whether endothel...

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Bibliographic Details

Published in:	Blood Advances
Main Authors:	Magdalena L. Bochenek, Tobias Bauer, Rajinikanth Gogiraju, Yona Nadir, Amrit Mann, Tanja Schönfelder, Leonie Hünig, Benjamin Brenner, Thomas Münzel, Philip Wenzel, Stavros Konstantinides, Katrin Schäfer
Format:	Article
Language:	English
Published:	Elsevier 2018-06-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2473952920309927