The cardiac METTL3/m6A pathway regulates the systemic response to Western diet

Regulation of organismal homeostasis in response to nutrient availability is a vital physiological process that involves interorgan communication. The role of the heart in controlling systemic metabolic health is not clear. Adopting a mouse model of diet-induced obesity, we found that the landscape...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Charles Rabolli, Jacob Z. Longenecker, Isabel S. Naarmann-de Vries, Joan Serrano, Jennifer M. Petrosino, George A. Kyriazis, Christoph Dieterich, Federica Accornero
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2025-06-01
Subjects:	Cardiology Muscle biology
Online Access:	https://doi.org/10.1172/jci.insight.188414