Levosimendan Relaxes Pulmonary Arteries and Veins in Precision-Cut Lung Slices - The Role of KATP-Channels, cAMP and cGMP.

Levosimendan is approved for left heart failure and is also used in right heart failure to reduce right ventricular afterload. Despite the fact that pulmonary arteries (PAs) and pulmonary veins (PVs) contribute to cardiac load, their responses to levosimendan are largely unknown.Levosimendan-induced...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Annette D Rieg, Rolf Rossaint, Eva Verjans, Nina A Maihöfer, Stefan Uhlig, Christian Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Online Access:http://europepmc.org/articles/PMC3688856?pdf=render