Drug Efflux Pump Inhibitors: A Promising Approach to Counter Multidrug Resistance in Gram-Negative Pathogens by Targeting AcrB Protein from AcrAB-TolC Multidrug Efflux Pump from <i>Escherichia coli</i>

Infections caused by multidrug resistance (MDR) of Gram-negative bacteria have become one of the most severe public health problems worldwide. The main mechanism that confers MDR to bacteria is drug efflux pumps, as they expel a wide range of compounds, especially antibiotics. Among the different ty...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Biology
المؤلف الرئيسي: Rawaf Alenazy
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2022-09-01
الموضوعات:
multidrug resistance
drug efflux pumps inhibitors
mechanisms of antibiotic resistance
superfamily efflux pump RND
AcrAB-TolC drug efflux complex
AcrB protein
الوصول للمادة أونلاين:https://www.mdpi.com/2079-7737/11/9/1328

الانترنت

https://www.mdpi.com/2079-7737/11/9/1328

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