Predicting MHC-I ligands across alleles and species: how far can we go?

Abstract Background CD8+ T-cell activation is initiated by the recognition of epitopes presented on class I major histocompatibility complex (MHC-I) molecules. Identifying such epitopes is useful for molecular understanding of cellular immune responses and can guide the development of personalized v...

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Bibliographic Details
Published in:Genome Medicine
Main Authors: Daniel M. Tadros, Julien Racle, David Gfeller
Format: Article
Language:English
Published: BMC 2025-03-01
Online Access:https://doi.org/10.1186/s13073-025-01450-8