Degradation of PARP1 by MARCHF3 in tumor cells triggers cCAS-STING activation in dendritic cells to regulate antitumor immunity in hepatocellular carcinoma
Background Resistance to immune checkpoint inhibitors (ICIs) significantly limits the efficacy of immunotherapy in patients with hepatocellular carcinoma (HCC). However, the mechanisms underlying immunotherapy resistance remain poorly understood. Our aim was to clarify the role of membrane-associate...
| 出版年: | Journal for ImmunoTherapy of Cancer |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
BMJ Publishing Group
2024-11-01
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| オンライン･アクセス: | https://jitc.bmj.com/content/12/11/e010157.full |