PIM kinase control of CD8 T cell protein synthesis and cell trafficking

Integration of kinase signalling networks co-ordinates the transcriptional, translational, and metabolic changes required for T cell activation and differentiation. This study explores the role of the Serine/Threonine kinases PIM1 and PIM2 in controlling mouse CD8 T lymphocyte antigen receptor-media...

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Bibliographic Details
Published in:eLife
Main Authors: Julia M Marchingo, Laura Spinelli, Shalini Pathak, Doreen A Cantrell
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Subjects:
T cell
PIM kinase
proteomics
protein translation
IL-2
IL-15
Online Access:https://elifesciences.org/articles/98622

Internet

https://elifesciences.org/articles/98622

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