The effect of iron status on gadolinium deposition in the rat brain: mechanistic implications

Introduction: Sites associated with gadolinium (Gd) deposition in the brain (e.g., the globus pallidus) are known to contain high concentrations of ferric iron. There is considerable debate over the mechanism of Gd deposition in the brain. The role of iron transport mechanisms in Gd deposition has n...

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Bibliographic Details

Published in:	Frontiers in Toxicology
Main Authors:	John P. Prybylski, Olivia Jastrzemski, Michael Jay
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-08-01
Subjects:	gadolinium toxicokinetics (TK) iron deficiency iron overload (IO) MRI
Online Access:	https://www.frontiersin.org/articles/10.3389/ftox.2024.1403031/full