Molecular mechanisms of resistance and treatment efficacy of clofazimine and bedaquiline against Mycobacterium tuberculosis

Clofazimine (CFZ) and bedaquiline (BDQ) are currently used for the treatment of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) strains. In recent years, adding CFZ and BDQ to tuberculosis (TB) drug regimens against MDR Mtb strains has significantly improved treatment results, but these i...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Md Mahmudul Islam, Md Shah Alam, Zhiyong Liu, Mst Sumaia Khatun, Buhari Yusuf, H. M. Adnan Hameed, Xirong Tian, Chiranjibi Chhotaray, Rajesh Basnet, Haftay Abraha, Xiaofan Zhang, Shahzad Akbar Khan, Cuiting Fang, Chunyu Li, Sohel Hasan, Shouyong Tan, Nanshan Zhong, Jinxing Hu, Tianyu Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	cross-resistance drug resistance mechanism of action molecular diagnostic regimens treatment
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2023.1304857/full