Sperm-borne microRNA-34c regulates maternal mRNA degradation and preimplantation embryonic development in mice

Abstract Background Studies have shown that sperm-borne microRNAs (miRNAs) are involved in mammalian preimplantation embryonic development. In humans, spermatozoan miR-34c levels are correlated with in vitro fertilization outcomes, such as embryo quality and the clinical pregnancy and live birth rat...

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Bibliographic Details

Published in:	Reproductive Biology and Endocrinology
Main Authors:	Long Cui, Li Fang, Lili Zhuang, Biwei Shi, Chao-Po Lin, Yinghui Ye
Format:	Article
Language:	English
Published:	BMC 2023-04-01
Subjects:	microRNA Sperm miR-34c Maternal mRNA degradation Preimplantation embryonic development
Online Access:	https://doi.org/10.1186/s12958-023-01089-3