Target identification and validation of the alpha7 nicotinic acetylcholine receptor as a potential therapeutic target in retinal disease

The role of acetylcholine (ACh) in visual processing in the mammalian retina has been the focus of research for many decades. Pioneering work on the localization of ACh discovered that the neurotransmitter is synthesized and stored in a distinct subpopulation of amacrine (starburst) cells. It has be...

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Bibliographic Details

Published in:	Frontiers in Ophthalmology
Main Author:	David M. Linn
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Subjects:	retina nicotinic acetylcholine receptor (nAChR) α7 nAChR retinal ganglion cell (RGC) neuroprotection neurogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fopht.2023.1190439/full