Accurate image derived input function in [18F]SynVesT-1 mouse studies using isoflurane and ketamine/xylazine anesthesia

Abstract Background Kinetic modeling in positron emission tomography (PET) requires measurement of the tracer plasma activity in the absence of a suitable reference region. To avoid invasive blood sampling, the use of an image derived input function has been proposed. However, an accurate delineatio...

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Bibliographic Details

Published in:	EJNMMI Physics
Main Authors:	Alan Miranda, Daniele Bertoglio, Steven Staelens, Jeroen Verhaeghe
Format:	Article
Language:	English
Published:	SpringerOpen 2023-12-01
Subjects:	Mouse [18F]SynVesT-1 Image derived input function Non-negative matrix factorization
Online Access:	https://doi.org/10.1186/s40658-023-00599-8