METTL1 gene polymorphisms synergistically confer hepatoblastoma susceptibility

Abstract Introduction Hepatoblastoma is a rare but devastating pediatric liver malignancy. Overexpressed methyltransferase-like 1 (METTL1) is a methyltransferase that catalyzes essential N7-methylguanosine (m7G) modification of eukaryotic mRNA. Accumulating evidence has revealed the oncogenic potent...

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Bibliographic Details

Published in:	Discover Oncology
Main Authors:	Lili Ge, Jinhong Zhu, Jiabin Liu, Li Li, Jiao Zhang, Jiwen Cheng, Yong Li, Zhonghua Yang, Suhong Li, Jing He, Xianwei Zhang
Format:	Article
Language:	English
Published:	Springer 2022-08-01
Subjects:	Hepatoblastoma Susceptibility METTL1 Polymorphism m7G modification
Online Access:	https://doi.org/10.1007/s12672-022-00545-7