Transient activation of notch signaling enhances endogenous stromal cell expansion and subsequent bone defect repair

Background: Following traumatic bone loss or removal of bone tumors, the failure of bone allograft transplantation for large bone defect repair remains a significant problem in orthopedics. Therefore, new strategies that can efficiently enhance allograft healing and long-term incorporation are criti...

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Bibliographic Details

Published in:	Journal of Orthopaedic Translation
Main Authors:	Guangxi Wang, Jinglong Yan, Hao Zhang, Patrick Massey, J. Steven Alexander, Christopher G. Kevil, Shane Barton, Yufeng Dong
Format:	Article
Language:	English
Published:	Elsevier 2021-11-01
Subjects:	Jagged1 Notch signaling Stromal cells Bone allograft
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X21000747