Effect of Combined Mycophenolate and Rapamycin Treatment on Kidney Fibrosis in Murine Lupus Nephritis

Background: A significant proportion of lupus nephritis patients develop chronic kidney disease (CKD) and progressive kidney fibrosis, for which there is no specific treatment. We previously reported that mycophenolate or rapamycin monotherapy showed comparable efficacy in suppressing kidney fibrosi...

全面介紹

書目詳細資料

發表在:	Frontiers in Pharmacology
Main Authors:	Chenzhu Zhang, Tsz Wai Tam, Mel KM Chau, Cristina Alexandra García Córdoba, Susan Yung, Tak Mao Chan
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2022-04-01
主題:	lupus nephritis rapamycin mycophenolate mesangial cells fibrosis
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fphar.2022.866077/full