The TORC2 component, Sin1, controls migration of anterior mesendoderm during zebrafish gastrulation.

TORC2 is a serine-threonine kinase complex conserved through evolution that recently emerged as a new regulator of actin dynamics and cell migration. However, knockout in mice of its core components Sin1 and Rictor is embryonic lethal, which has limited in vivo analyses. Here, we analysed TORC2 func...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Julien G Dumortier, Nicolas B David
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118474&type=printable