Natural infection by Zika virus but not DNA vaccination consistently elicits antibodies that compete with two potently neutralising monoclonal antibodies targeting distinct epitopesResearch in context

Summary: Background: Autochthonous transmission of Zika virus (ZIKV) has been reported in 87 countries since 2015. Although most infections are mild, there is risk of Guillain-Barré syndrome and adverse pregnancy outcomes. Vaccines are urgently needed to prevent Zika, but sufficient understanding o...

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Bibliographic Details

Published in:	EBioMedicine
Main Authors:	Teresa C. Smith, Daniel O. Espinoza, Yerun Zhu, Jaime A. Cardona-Ospina, Natalie M. Bowman, Sylvia Becker-Dreps, Nadine Rouphael, Alfonso J. Rodriguez-Morales, Filemon Bucardo, Srilatha Edupuganti, Lakshmanane Premkumar, Mark J. Mulligan, Aravinda M. de Silva, Matthew H. Collins
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Subjects:	Zika Vaccinology Virus neutralisation Type-specific antibody Humoral immunity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396423004413