Kaempferol Ameliorates Oxygen-Glucose Deprivation/Reoxygenation-Induced Neuronal Ferroptosis by Activating Nrf2/SLC7A11/GPX4 Axis

Kaempferol has been shown to protect cells against cerebral ischemia/reperfusion injury through inhibition of apoptosis. In the present study, we sought to investigate whether ferroptosis is involved in the oxygen-glucose deprivation/reperfusion (OGD/R)-induced neuronal injury and the effects of kae...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Yuan Yuan, Yanyu Zhai, Jingjiong Chen, Xiaofeng Xu, Hongmei Wang
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Subjects:	ischemic stroke kaempferol Nrf2 GPX4 lipid peroxidation ferroptosis
Online Access:	https://www.mdpi.com/2218-273X/11/7/923