Liver as a new target organ in Alzheimer’s disease: insight from cholesterol metabolism and its role in amyloid-beta clearance

Alzheimer’s disease, the primary cause of dementia, is characterized by neuropathologies, such as amyloid plaques, synaptic and neuronal degeneration, and neurofibrillary tangles. Although amyloid plaques are the primary characteristic of Alzheimer’s disease in the central nervous system and periphe...

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Bibliographic Details

Published in:	Neural Regeneration Research
Main Authors:	Beibei Wu, Yuqing Liu, Hongli Li, Lemei Zhu, Lingfeng Zeng, Zhen Zhang, Weijun Peng
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2023-12-01
Subjects:	abca1 alzheimer’s disease amyloid-beta apolipoprotein e cholesterol metabolism liver liver x receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid
Online Access:	https://journals.lww.com/10.4103/1673-5374.391305