Efficacy of dupilumab for airway hypersecretion and airway wall thickening in patients with moderate-to-severe asthma: A prospective, observational study

Background: Dupilumab has clinical effects in patients with moderate-to-severe asthma. When considering interleukin (IL)-4 and IL-13 signaling, effects of dupilumab on airway mucus hypersecretion and airway remodeling are expected, but they have been reported in only a few short-term studies. Its ef...

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Bibliographic Details

Published in:	Allergology International
Main Authors:	Tomoko Tajiri, Motohiko Suzuki, Hirono Nishiyama, Yoshiyuki Ozawa, Ryota Kurokawa, Norihisa Takeda, Keima Ito, Kensuke Fukumitsu, Yoshihiro Kanemitsu, Yuta Mori, Satoshi Fukuda, Takehiro Uemura, Hirotsugu Ohkubo, Masaya Takemura, Ken Maeno, Yutaka Ito, Tetsuya Oguri, Kenji Izuhara, Akio Niimi
Format:	Article
Language:	English
Published:	Elsevier 2024-07-01
Subjects:	Asthma Airway hyperresponsiveness Airway hypersecretion Airway remodeling Dupilumab
Online Access:	http://www.sciencedirect.com/science/article/pii/S1323893024000169