Maximizing oxaliplatin's impact on EGFR + colorectal cancer through targeted extracellular vesicles

Abstract Purpose To investigate the ability of extracellular vesicles (EVs) to deliver oxaliplatin to epidermal growth factor receptor (EGFR+) colorectal cancer cells and increase oxaliplatin’s cytotoxicity. Method Oxaliplatin was passively loaded into a stable cell line expressing cetuximab in memb...

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Bibliographic Details
Published in:Cancer Nanotechnology
Main Authors: Shang-Tao Chien, Yi-Jung Huang, Ming-Yii Huang, Yi-Ping Fang, Shi-Wei Chao, Chia-Tse Li, Wun-Ya Jhang, Yun-Han Hsu, Shuo-Hung Wang, Chih-Hung Chuang
Format: Article
Language:English
Published: BMC 2024-08-01
Subjects:
Extracellular vesicles
Oxaliplatin delivery
EGFR+ colorectal cancer
Online Access:https://doi.org/10.1186/s12645-024-00284-0

Internet

https://doi.org/10.1186/s12645-024-00284-0

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